GL Carrington et.al. in 1925, first identified the association of Salmonella osteomyelitis in sickle cell anemia patients. There are several sickle cell hemoglobinopathies, namely, HbSS, HbSC, and HbSthalassemia. Sickle cell anemia leads to intravascular sickling in the bowel. This causes ischemia of the bowel and devitalization and transient mucosal barrier breakdown. This leads to repeated… Continue reading Salmonella osteomyelitis in sickle cell disease